MICROBIOLOGICAL EVALUATION OF NOVEL BIS-QUATERNARY AMMONIUM COMPOUNDS: CLINICAL STRAINS, BIOFILMS, AND RESISTANCE STUDY

Microbiological Evaluation of Novel Bis-Quaternary Ammonium Compounds: Clinical Strains, Biofilms, and Resistance Study

This work is devoted to the investigation of biocidal properties of quaternary ammonium compounds (QACs) based on pyridine structures with aromatic spacers, and their widely known analogs, against clinically significant microorganisms.This study Styling gel is focused on investigating their antimicrobial activity (minimum inhibitory concentrations

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MCM8- and MCM9 Deficiencies Cause Lifelong Increased Hematopoietic DNA Damage Driving p53-Dependent Myeloid Tumors

Summary: Hematopoiesis is particularly sensitive to DNA damage.Myeloid tumor incidence increases in patients with DNA repair defects and after chemotherapy.It is not known why hematopoietic cells are highly vulnerable to DNA damage.Addressing this question is complicated by the paucity of mouse models of hematopoietic malignancies due to defective

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